Research material profile
Selank
Synthetic tuftsin-derived heptapeptide
Selank is a seven-amino-acid peptide derived from the tuftsin sequence. Published mechanistic work has examined GABA-receptor binding and neurotransmission-related gene expression, mostly in laboratory and animal systems.
- Identity shorthand
- TKPRPGP
- Evidence map
- Mechanistic and animal-model evidence
- Public page scope
- Identity and literature context; no purchase offer
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Plain-language identity
What Selank is
Selank is a seven-amino-acid peptide derived from the tuftsin sequence. Published mechanistic work has examined GABA-receptor binding and neurotransmission-related gene expression, mostly in laboratory and animal systems.
- Research class
- Synthetic tuftsin-derived heptapeptide
- Sequence / identity shorthand
TKPRPGP- Evidence map
- Mechanistic and animal-model evidence
The literature may refer to Selank free base, acetate, or other characterized preparations. Counter-ion and lot identity should be kept explicit in any research record.
What researchers examine
- GABA-receptor binding and proposed allosteric modulation in membrane preparations.
- Short-term neurotransmission-related gene-expression changes in rat frontal cortex.
- How molecular form, model system, and regional literature affect interpretation.
How to read the evidence
- A 2016 rat study measured time-dependent expression changes in a panel of neurotransmission-related genes after Selank or GABA exposure.
- A 2018 receptor-binding study described concentration-dependent modulation of radiolabeled GABA binding.
- Mechanistic similarity does not establish equivalence to a medicine, a clinical outcome, or safety for personal use.
What this evidence does not establish
- Much of the accessible literature is mechanistic, animal-based, or regionally published; broad clinical conclusions are not warranted.
- FDA identifies limited safety information and immunogenicity and peptide-impurity concerns for compounded drugs containing Selank acetate.
- This catalog material is not a drug, supplement, or product for administration.
Documentation checklist
- Record sequence, counter-ion or salt form, SKU, lot, nominal quantity, and analytical method.
- Treat gene-expression and receptor-binding results as model-specific measurements.
- Keep identity, purity, quantity, endotoxin, and sterility questions analytically separate.
Primary and official sources
Links are provided for source review. A citation is not an endorsement of nonresearch use.
- Volkova et al. — Selank and neurotransmission-related gene expression (2016)Rat frontal-cortex gene-expression study.
- Vyunova et al. — Selank and GABA-receptor binding (2018)Radioligand receptor study.
- FDA — bulk substances that may present significant safety risksRegulatory context for compounded drugs containing Selank acetate.