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LC-MS vs HPLC: How Peptide Identity Testing Is Documented

LC-MS and HPLC are common labels on peptide documentation. They do not mean the same thing, and they should be read in the context of the COA or specification sheet where they appear.

HPLC in documentation

HPLC is often associated with purity-related documentation. A COA may list an HPLC purity result, method label, chromatogram reference, or acceptance criteria.

LC-MS in documentation

LC-MS or MS labels are often associated with identity-related documentation. They may appear near molecular weight, identity confirmation, or method notes depending on the report format.

Why both fields matter

Purity and identity answer different documentation questions. A strong procurement record should connect product name, SKU, batch number, purity result, identity field, and method labels in one traceable file.

Buyer checklist

  • Confirm the document belongs to the product and batch.
  • Review both identity and purity fields when available.
  • Read method labels with the result fields they support.
  • Request clarification if the document does not match the purchase record.

COA Catalog